Urban Milan Ph.D.

Journals

PERLÍKOVÁ, P., M. KVASNICA, M. URBAN, M. HAJDÚCH, J. ŠAREK
2-Deoxyglycoside Conjugates of Lupane Triterpenoids with High Cytotoxic Activity-Synthesis, Activity, and Pharmacokinetic Profile. Bioconjugate Chemistry. 2019, 30(11), 2844-2858, ISSN: 1043-1802, PMID: 31553559,
HODOŇ, J., L. BORKOVÁ, J. POKORNÝ, A. KAZAKOVA, M. URBAN
Design and synthesis of pentacyclic triterpene conjugates and their use in medicinal research. European Journal of Medicinal Chemistry. 2019, 182, 111653, ISSN: 0223-5234, PMID: 31499360,
POKORNÝ, J., S. KRAJČOVIČOVÁ, M. HAJDÚCH, M. HOLOUBEK, S. GURSKÁ, P. DŽUBÁK, T. VOLNÁ, I. POPA, M. URBAN
Triterpenic azines, a new class of compounds with selective cytotoxicity to leukemia cells CCRF-CEM. Future Medicinal Chemistry. 2018, 10(5), 483-491, ISSN: 1756-8919, PMID: 29424548,

Master mentorship

Borková Lucie Ph.D.

Modification of the position 2 in betulin, allobetulin and betulinic acid with polar substituents

Status: Graduated from 2012 to 2014.
Hodoň Jiří

Cytotoxic active triterpenes and their mechanism of action

Status: Graduated from 2015 to 2017.
Schwarzová Agnes

Preparation of analogues of platanic and betulinic acid with cytotoxic effect

Status: Ongoing from 2022.

Bachelor mentorship

Kúdelová Kristína

Synthesis of new semisynthetic derivatives of betulin

Status: Graduated from 2021 to 2022.
Šťastná Barbora

Synthesis of triterpenes suitable for their visualization in the cell

Status: Graduated from 2021 to 2022.
Novák Jakub

Visualization of triterpenes in tumor cells

Status: Graduated from 2021 to 2023.

Open positions

Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training