Urban Milan Ph.D.

Journals

POKORNÝ, J., D. OLEJNÍKOVÁ, I. FRYDRYCH, B. LIŠKOVÁ, S. GURSKÁ, S. BENICKÁ, J. ŠAREK, J. KOTULOVÁ, M. HAJDÚCH, P. DŽUBÁK, M. URBAN
Substituted dienes prepared from betulinic acid - Synthesis, cytotoxicity, mechanism of action, and pharmacological parameters. European Journal of Medicinal Chemistry. 2021, 224, 113706, ISSN: 0223-5234, PMID: 34311159,
BACHOŘÍK, J., M. URBAN
Biocatalysis in the Chemistry of Lupane Triterpenoids. Molecules. 2021, 26(8), 2271, ISSN: 1420-3049, PMID: 33919839,  PDF.
GONZALES, G., J. HODOŇ, A. KAZAKOVA, C. D´ACUNTO, P. KANOVSKY, M. URBAN, M. STRNAD
Novel pentacyclic triterpenes exhibiting strong neuroprotective activity in SH-SY5Y cells in salsolinol- and glutamate-induced neurodegeneration models. European Journal of Medicinal Chemistry. 2021, 213, 113168, ISSN: 0223-5234, PMID: 33508480,

Doctoral mentorship

Borková Lucie Ph.D.

Modification of triterpenes with the use of transition metal catalyzed reactions and nucleophilic substitution

Stav: Absolvoval od 2014 do 2018.
Pokorný Jan

Modifications of double bonds in triterpenes with antitumor activity

Stav: Absolvoval od 2015 do 2022.
Hodoň Jiří

Cytotoxic active triterpenes and their mechanism of action

Stav: Probíhající od 2017.

Master mentorship

Olejníková Denisa

Synthesis of new lupane derivatives modified at position 20 or 30

Stav: Absolvoval od 2018 do 2020.
Šidová Veronika

Synthesis of new cytotoxic triterpenoid derivatives using click chemistry

Stav: Absolvoval od 2013 do 2015.
Zoufalý Pavel

Exploraton of click reaction approach in triterpenoids containing propargyl substituent

Stav: Absolvoval od 2014 do 2016.

Bachelor mentorship

Horka Vladimír

Conjugates of betulin prepared by cycloaddition reactions

Stav: Absolvoval od 2016 do 2018.
Olejníková Denisa

Synthesis of new lupane derivatives modified at position 20 or 30

Stav: Absolvoval od 2016 do 2018.
Orság Šimon

Preparation of new heterocyclic derivatives of triterpene

Stav: Absolvoval od 2018 do 2020.

Open positions

Projekt: Research and development of agents for cancer, neurodegenerative and infectious diseases
Vedoucí: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
K dispozici: 5
Určeno pro: Doktorské studium