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Dömling Alexander PhD.

Journals

RAMMAH, M., A. REYES ROMERO, N. HALABI, S. ABUAQUEL, A. GUENNOUN, A. DÖMLING, J. SHAN, L. CHOUCHANE
A small‑molecule HDAC/PDE modulator activates human adipocyte UCP1 and resolves inflammatory signaling. Journal of Translational Medicine. 2026, ISSN: 1479-5876, PMID: 41787480,  PDF.
KHOSRAVIFARD, S., S. HOSSEINKHANI, N. BAKHTIARY, M. PEYVANDI, A. DÖMLING
Disruption of NLRP3 inflammasome assembly via ligand-induced remodeling of pyrin domain interfaces. Scientific Reports. 2026, ISSN: 2045-2322, PMID: 41513945,  PDF.
PATIL, P., E. INGENITO, R. FUSCO, I. CAPRIELLO, Z. GUAN, A. BHALKIKAR, J. GIBBONS, T. KORBA, S. BASKHYRTSEV, O. TKACHENKO, A. DÖMLING
Precipitation-first synthesis and deep profiling of a 1200-member acrylamide library for covalent drug discovery. Green Chemistry . 2025, 27(45), 14640-14647, ISSN: 1463-9262, PMID: 41181219,  PDF.

Postdoctoral mentorship

Reyes Romero Atilio Ph.D.

Accellerated Drug Discovery and Screening

Stav: Probíhající.

Doctoral mentorship

Masineni Samantha

Synthesis and characterization of 2D nanoplatforms as active drug carriers

Stav: Probíhající od 2024.
Mukim Mayur Shashikan

Synthesis and characterization of 2D nanoplatforms as active drug carriers

Stav: Probíhající od 2024.
Salama Kaoud MSc.

Synthesis and characterization of 2D nanoplatforms as active drug carriers

Stav: Probíhající od 2024.

Open positions

Projekt: New anti-inflammatory small molecules
Vedoucí: Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Microsynthesis of drug candidates in medicinal chemistry
Vedoucí: Dömling Alexander PhD.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: Innovative approaches to modifiers of protein interactions
Vedoucí: Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Utilization of the space of unprecedented covalent inhibitors
Vedoucí: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Discovery of new antibacterial substances
Vedoucí: Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Discovery of new antitumor substances
Vedoucí: Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Innovative drugs for Parkinson's disease
Vedoucí: Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Innovative medicinal chemistry
Vedoucí: Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Decoding the binding principles of small molecules to RNA
Vedoucí: Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Targeted approaches to covalent inhibitors
Vedoucí: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Synthesis of kinase inhibitors and their phenotypic chemoproteomic evaluation
Vedoucí: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Modification of biologically active molecules leading to their improvement pharmacological properties
Vedoucí: Dömling Alexander PhD.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: New methods of targeted protein degradation
Vedoucí: Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Drug repurposing for the treatment and prevention of diseases
Vedoucí: Hajdúch Marián M.D., Ph.D., Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: New chemoinformatic approaches to fragment-based drug discovery
Vedoucí: Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Development of drugs in the field of small molecules 2 places in full-time study
Vedoucí: Dömling Alexander PhD., Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study