Frydrych Ivo Ph.D.

Telefon: +420 585 632 145

Skupiny: IMTM, LEM, POSTDOKTORSKÝ STUDENT, PERSONÁL

Stav: Ongoing.

Researcher experienced in the field of cellular biology, microscopy, and flow cytometry with the main focus on studying the mechanism of action of newly synthesized cytotoxic compounds as potential anticancer drugs. GMO advisor at IMTM. Published >25 scientific papers and books/chapters, >312 SCI citations, H-index 10.

HODOŇ, J., I. FRYDRYCH, Z. TRHLÍKOVÁ, J. POKORNÝ, L. BORKOVÁ, S. BENICKÁ, M. VLK, B. LIŠKOVÁ, A. KUBÍČKOVÁ, M. MEDVEDÍKOVÁ, M. PISÁR, J. ŠAREK, V. DAS, A. LIGASOVÁ, K. KOBERNA, P. DŽUBÁK, M. HAJDÚCH, M. URBAN

Triterpenoid pyrazines and pyridines - Synthesis, cytotoxicity, mechanism of action, preparation of prodrugs. European Journal of Medicinal Chemistry. 2022, 243, 114777, ISSN: 0223-5234, PMID: 36174412, PDF.

SMEŠNÝ TRTKOVÁ, K., P. LUŽNÁ, D. WEISER DROZDKOVA, K. ČÍŽKOVÁ, L. JANOVSKA, J. GURSKÝ, D. PRUKOVA, I. FRYDRYCH, M. HAJDÚCH, J. MINARIK

The epigenetic impact of suberohydroxamic acid and 5‑Aza‑2'‑deoxycytidine on DNMT3B expression in myeloma cell lines differing in IL‑6 expression. Molecular Medicine Reports. 2022, 26(4), 321, ISSN: 1791-2997, PMID: 36043519,

POKORNÝ, J., D. OLEJNÍKOVÁ, I. FRYDRYCH, B. LIŠKOVÁ, S. GURSKÁ, S. BENICKÁ, J. ŠAREK, J. KOTULOVÁ, M. HAJDÚCH, P. DŽUBÁK, M. URBAN

Substituted dienes prepared from betulinic acid - Synthesis, cytotoxicity, mechanism of action, and pharmacological parameters. European Journal of Medicinal Chemistry. 2021, 224, 113706, ISSN: 0223-5234, PMID: 34311159,

Frydrych Ivo Ph.D.

Postdoctoral training

O mně

Journals