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Academic title: Associate Professor
Phone: +420 585632137
Groups: IMTM, LEM, POSTDOCTORAL FELLOW, STAFF

About me

Scientist and medical professional mainly involved in molecular and translational medicine (disease area paediatric, oncology and medical genetics). Experienced in project management and certification processes, involved as investigator in more than 20 national and international projects, co-founder of spin-off company focused on manufacturing of molecular diagnostics. 
Published more than >65 papers, >7books/chapters, >2 patents,  >290 oral/poster presentations, >1000 SCI citations, H-index 12

Specialties: 
Molecular and translational medicine
Pediatrics, Oncology and Medical Genetics
Circulating tumor cells detection
Molecular profilling of tumors
Prognostic, predictive and diagnostic biomarkers

Responsibility for transcriptomic sequencing, circulating tumor cells detection, PCR based methods, gene expression profiling, SNP and CNV arrays. Biostatistical analyses. Biomedical project coordinator. Quality manager (ISO 15189). Teaching and examination of students, tutor for Bc., MSc. and PhD. students.

Journals

SMOLKA, V., D. FRIEDECKÝ, J. KOLAROVA, O. TKACIK, H. FOLTENOVA, V. BEKÁREK, P. VRTEL, J. SROVNAL
Aminoacylase 1 deficiency: case report on three affected siblings. AME Case Reports. 2023, 8, 18, ISSN: 2523-1995, PMID: 38234346,  PDF.
SPURNA, Z., P. CAPKOVA, L. PUNOVA, J. DUCHOSLAVOVÁ, D. ALEKSIJEVIC, J. VENHACOVA, J. SROVNAL, J. STELLMACHOVA, V. CURTISOVA, V. BITNEROVA, K. KOLARIKOVA, M. JANÍKOVÁ, R. KRATOCHVILOVA, P. VRTEL, R. VODICKA, R. VRTEL, J. ZAPLETALOVÁ
Clinical-genetic analysis of selected genes involved in the development of the human skeleton in 128 Czech patients with suspected congenital skeletal abnormalities. Gene. 2024, 892, 147881, ISSN: 0378-1119, PMID: 37806643,
VECERA, L., P. PRASIL, J. SROVNAL, E. BERTA, M. VIDLAŘOVÁ, T. GABRHELIK, P. KOUŘILOVÁ, M. LOVEČEK, P. SKALICKÝ, J. ŠKARDA, Z. KALA, P. MICHALEK, M. HAJDÚCH
Morphine Analgesia, Cannabinoid Receptor 2, and Opioid Growth Factor Receptor Cancer Tissue Expression Improve Survival after Pancreatic Cancer Surgery. Cancers. 2023, 15(16), 4038, ISSN: 2072-6694, PMID: 37627066,  PDF.

Books & book chapters

Laboratory Techniques in Cellular and Molecular Medicine, 1.vyd., Olomouc, Palacky University, 2021, 436 s, Dedication: LO1304, ISBN: 978-80-244-6049-9,
Elektrochemické metody, (bio)senzory a čipové platformy, 1.vyd., korigovaný dotisk, Olomouc, Univerzita Palackého v Olonouci, 2021, 2.3, 43-52, ISBN: 978-80-244-3951-8,
Onkogenetika, 1.vyd., Olomouc, Univerzita Palackého v Olomouci, 2018, 109-116, ISBN: 978-80-244-5368-2,

Doctoral mentorship

Stejskal Pavel MSc

Circulating tumor cells detection

Status: Ongoing from 2020.

Sekyrová Anna MSc.

Liquid Biopsies in Clinical and Experimental Oncology

Status: Ongoing from 2024.

Master mentorship

Slavík Hanuš M.Sc.

Effect of analgesia on circulating tumor cells levels in colorectal cancer patients

Status: Graduated from 2012 to 2014.

Juřicová Markéta

Mechanism of phenretinide action and effect on miRNA expression in cystic fibrosis models

Status: Graduated from 2019 to 2021.

Rožková Markéta

Molecular characterization of circulating tumor cells in cancer patients

Status: Graduated from 2022 to 2023.

Bachelor mentorship

Svatošová Barbora

Detection of somatic mutations and selected cytogenetic changes in gliomas

Status: Graduated from 2021 to 2023.

Mikuláštíková Michaela

Revision of the variants of unclear significance (VUS) in patients tested for hereditary cancer syndromes in the context of the results of the A-C-G-T project

Status: Graduated from 2021 to 2023.

Resutíková Lucie

Telomerase in solid tumors

Status: Graduated from 2008 to 2008.

Open positions

2 Biomarkers: Identification and validation
Project: New prognostic and predictive factors in solid tumors
Supervisors: Srovnal Josef M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time or combined form of study
Project: Liquid biopsies in experimental and clinical oncology
Supervisors: Srovnal Josef M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time or combined form of study
5 Molecular and Translational Medicine
Project: Diagnosis and treatment of rare diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D., Adam Tomáš Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 full-time positions
Project: Liquid biopsies in experimental and clinical oncology
Supervisors: Srovnal Josef M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 full-time positions
Project: Diagnosis and treatment of rare diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of molecular targets and mechanisms of resistance in antitumor drugs
Supervisors: Srovnal Josef M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: New prognostic and predictive factors in solid tumors
Supervisors: Srovnal Josef M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 full-time positions