Jakubcová Nikola

Akademický titul: Mgr.

Telefon: + 420 585 632 183

Skupiny: CHEMIE, IMTM, MEDCHEM, PERSONÁL

In our research, we focus on the preparation of semi-synthetic derivatives of triterpenes with the aim of improving their biological properties. I am currently focusing on the preparation of heterocyclic derivatives of triterpenic acids with potential cytotoxic activity.

BORKOVÁ, L., I. FRYDRYCH, B. VRÁNOVÁ, N. JAKUBCOVÁ, B. LIŠKOVÁ, P. DŽUBÁK, P. PAVLIŠ, M. HAJDÚCH, M. URBAN

Lupane derivatives containing various aryl substituents in the position 3 have selective cytostatic effect in leukemic cancer cells including resistant phenotypes. European Journal of Medicinal Chemistry. 2022, 244, 114850, ISSN: 0223-5234, PMID: 36283179,

BORKOVÁ, L., I. FRYDRYCH, N. JAKUBCOVÁ, R. ADÁMEK, B. LIŠKOVÁ, S. GURSKÁ, M. MEDVEDÍKOVÁ, M. HAJDÚCH, M. URBAN

Synthesis and biological evaluation of triterpenoid thiazoles derived from betulonic acid, dihydrobetulonic acid, and ursonic acid. European Journal of Medicinal Chemistry. 2019, 185, 111806, ISSN: 0223-5234, PMID: 31677446,

Jakubcová Nikola

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