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Akademický titul: Prof. Dr.
Telefon: +420 588444231, +420 585632152
Skupiny: IMTM, METABOLOMIKA, PERSONÁL

O mně

Senior researcher, Professor, Biochemistry and Metabolomics

Main areas of research

Prof. Tomas Adam started working in diagnosing metabolic diseases as well as in development of diagnostic biochemical methods based on modern separation and mass spectrometry techniques. This led to subsequent development of metabolomic laboratory and relevant working pipelines.  He is involved in research of nucleotide metabolism in relation to inherited metabolic disorders, expanded newborn metabolic screening, developing novel statistical approaches to metabolic data and drug metabolism research in relation to cancer. In the last period he is focused on clinical applications and data analysis in metabolomics.

From a technological point of view is skilled in techniques such as liquid chromatography, capillary electrophoresis, mass spectrometry (QqQ, Orbitrap, ESI, high-throughput flow injection analysis, MS2/MS3 HR/AM fragmentation).

Last couple of years he has focused on metabolomics (targeted/untargeted approach - data processing, interpretation, analysis of bodyfluids, cells, tissues – clinical applications).

Journals

DE SOUSA, J., O. VENCALEK, K. HRON, J. VÁCLAVÍK, D. FRIEDECKÝ, T. ADAM
Bayesian multiple hypotheses testing in compositional analysis of untargeted metabolomic data. Analytica Chimica Acta. 2020, 1097, 49-61, ISSN: 0003-2670, PMID: 31910969,
FRIEDECKÁ, J., M. JORENEK, K. POSPISKOVA, L. NAJDEKR, L. ZAJONCOVA, D. FRIEDECKÝ, T. ADAM
Urease-immobilized magnetic microparticles in urine sample preparation for metabolomic analysis by gas chromatography-mass spectrometry. Journal of Chromatography. A. 2019, 1605, 360355, ISSN: 0021-967, PMID: 31315811,
MÁDROVÁ, L., M. KRIJT, V. BARESOVA, J. VÁCLAVÍK, D. FRIEDECKÝ, D. DOBEŠOVÁ, O. SOUCKOVA, V. SKOPKOVA, T. ADAM, M. ZIKANOVA
Mass spectrometric analysis of purine de novo biosynthesis intermediates. PLOS One. 2018, 13(12), e0208947, ISSN: 1932-6203, PMID: 30532129,  PDF.

Volná místa

1 Lékařská biologie
Projekt: Cellular fluxomic analysis for the research of pathobiochemical processes
Vedoucí: Adam Tomáš Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 místo v prezenční nebo kombinované formě studia
1 Molecular and Translational Medicine
Projekt: Cellular fluxomic analysis for research of pathobiochemical processes
Vedoucí: Adam Tomáš Ph.D.
K dispozici: 1
Určeno pro: Doctoral training
1 Molekulární a translační medicína
Projekt: Diagnosis and treatment of rare diseases
Vedoucí: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D., Adam Tomáš Ph.D.
K dispozici: 3
Určeno pro: Doktorské studium
Souhrn: 3 místa na plný úvazek