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Akademický titul: Prof. Dr.
Telefon: +420 588444231, +420 585632152
Skupiny: IMTM, METABOLOMIKA, PERSONÁL

O mně

Senior researcher, Professor, Biochemistry and Metabolomics

Main areas of research

Prof. Tomas Adam started working in diagnosing metabolic diseases as well as in development of diagnostic biochemical methods based on modern separation and mass spectrometry techniques. This led to subsequent development of metabolomic laboratory and relevant working pipelines.  He is involved in research of nucleotide metabolism in relation to inherited metabolic disorders, expanded newborn metabolic screening, developing novel statistical approaches to metabolic data and drug metabolism research in relation to cancer. In the last period he is focused on clinical applications and data analysis in metabolomics.

From a technological point of view is skilled in techniques such as liquid chromatography, capillary electrophoresis, mass spectrometry (QqQ, Orbitrap, ESI, high-throughput flow injection analysis, MS2/MS3 HR/AM fragmentation).

Last couple of years he has focused on metabolomics (targeted/untargeted approach - data processing, interpretation, analysis of bodyfluids, cells, tissues – clinical applications).

Journals

ZEZULOVÁ, M., M. BARTOUŠKOVÁ, E. HLIDKOVA, J. JURANOVA, B. CERVINKOVA, E. KASALOVA, T. ADAM, L. KUJOVSKA KRCMOVA, D. SOLICHOVA, K. CWIERTKA, D. VRÁNA, B. MELICHAR
Prognostic significance of serum and urinary neopterin concentrations in patients with rectal carcinoma treated with chemoradiation. Anticancer Research. 2016, 36(1), 287-292, ISSN: 0250-7005, PMID: 26722055,
FRIEDECKÝ, D., K. MIČOVÁ, E. FABER, M. HRDA, J. ŠIROKÁ, T. ADAM
Detailed study of imatinib metabolization using high-resolution mass spectrometry. Journal of Chromatography. 2015, 1409(-), 173-181, ISSN: 0021-9673, PMID: 26199102,
ZEZULOVÁ, M., M. BARTOUŠKOVÁ, E. HLIDKOVA, T. ADAM, L. KUJOVSKA KRCMOVA, B. CERVINKOVA, D. SOLICHOVA, M. ZLEVOROVA, K. CWIERTKA, D. FRIEDECKÝ, D. VRÁNA, B. MELICHAR
Citrulline as a biomarker of gastrointestinal toxicity in patients with rectal carcinoma treated with chemoradiation. Clinical Chemistry and Laboratory Medicine. 2015, 54(2), 305-314, ISSN: 1434-6621, PMID: 26167980,

Volná místa

1 Lékařská biologie
Projekt: Cellular fluxomic analysis for the research of pathobiochemical processes
Vedoucí: Adam Tomáš Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 místo v prezenční nebo kombinované formě studia
1 Molecular and Translational Medicine
Projekt: Cellular fluxomic analysis for research of pathobiochemical processes
Vedoucí: Adam Tomáš Ph.D.
K dispozici: 1
Určeno pro: Doctoral training
1 Molekulární a translační medicína
Projekt: Diagnosis and treatment of rare diseases
Vedoucí: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D., Adam Tomáš Ph.D.
K dispozici: 3
Určeno pro: Doktorské studium
Souhrn: 3 místa na plný úvazek