Slavkovský Rastislav Ph.D.

Slavkovský Rastislav Ph.D.'s picture
Academic Title: Ing.
Phone: +420 585632186
LinkedIn

I am a research scientist passionate for molecular and cellular biology, DNA microarray, Next-Gen sequencing and gene-expresion analysis. I always enjoy datamining of biologicaly relevant data and the comparison of data with already known information. I was involved in different studies such as wound healing characterization, experimental diabetes mellitus, effect of potentially active compounds or radiation on cells in vitro. I was responsible for a developement of a small laboratory for studing microbial biofilm in vitro. Currently, with my collegues, we are working on the developement of methods for predicive diagnostics of colorectal cancer, cardiomyopathy related genes and methylome profiling.


Publications (Impact Factor Journals):

  • [5]
    KLEIN, P., M. SOJKA, J. KUČERA, J. MATONOHOVA, V. PAVLIK, J. NEMEC, G. KUBICKOVA, R. SLAVKOVSKÝ, K. SZUSZKIEWICZ, P. DANEK, M. ROZKOT a V. VELEBNY. A porcine model of skin wound infected with a polybacterial biofilm. Biofouling. 2018, 34(2), 226-236. ISSN 0892-7014. IF: 3.080. PMID: 29405092
  • [4]
    MODER, M., G. VELIMEZI, M. OWUSU, A. MAZOUZI, M. WIEDNER, J. FERREIRA DA SILVA, L. ROBINSON-GARCIA, F. SCHISCHLIK, R. SLAVKOVSKÝ, R. KRALOVICS, B. SCHUSTER, C. BOCK, T. IDEKER, S. JACKSON, J. MENCHE a J. LOIZOU. Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia. Nature Communications. 2017, 8(1), 1238. ISSN 2041-1723. IF: 12.124. PMID: 29089570
  • [3]
    PLEVOVA, P., M. PAPRSKÁŘOVÁ, P. TVRDA, P. TURSKA, R. SLAVKOVSKÝ a E. MRAZKOVA. STRC Deletion is a Frequent Cause of Slight to Moderate Congenital Hearing Impairment in the Czech Republic. Otology & Neurotology. 2017, 38(10), e393-e400. ISSN 1531-7129. IF: 2.024. PMID: 28984810
  • [2]
    KLASKOVA, E., J. DRÁBEK, M. HOBZOVA, V. SMOLKA, M. SEDA, J. HYJÁNEK, R. SLAVKOVSKÝ, J. STRÁNSKÁ a M. PROCHAZKA. Significant phenotype variability of congenital central hypoventilation syndrome in a family with polyalanine expansion mutation of the PHOX2B gene. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2016, 160(4), 495-498. ISSN 1213-8118 . IF: 0.894. PMID: 27485184
  • [1]
    STRÁNSKÁ, J., S. JANČÍK, R. SLAVKOVSKÝ, V. HOLINKOVÁ, M. RABČANOVÁ, P. VOJTA, M. HAJDÚCH a J. DRÁBEK. Whole genome amplification induced bias in the detection of KRAS-mutated cell populations during colorectal carcinoma tissue testing. Electrophoresis. 2015, 36(6), 937-40. ISSN 0173-0835. IF: 2.482. PMID: 25655305

Publications (Other Reviewed Journals):



Master students mentor:

[6] Barbora Koblihová, Optimization of somatic mutation diagnostics in selected tumors with help of massive parallel sequencing,
status: Ongoing, from: 2017
[5] Lenka Vysloužilová, Significance assessment of gene variants identified by next-generation sequencing associated with inherited cardiomyopathies,
status: Ongoing, from: 2017
[4] Lucie Kotková, Optimization of library preparation for NGS,
status: Graduated, from: 2015 to 2017
[3] Gabriela Fryčová, Methylome profiling in cancer cells for identification of bevacizumab response biomarkers,
status: Ongoing, from: 2016
[2] Veronika Věnsková, Diagnostics of mutations in RAS family oncogenes in tumors using next-generation sequencing,
status: Graduated, from: 2014 to 2016
[1] Natália Podhorská, Epigenetic changes detection in cancer cells,
status: Ongoing, from: 2015


Bachelor students mentor:

[3] Lucia Csergeova, Genotyping of tumor biomarkers using novel multi-parallel sequencing technologies with an emphasis on ultra sesnsitive typing of circulating tumor DNA,
status: Ongoing, from: 2017
[2] Gabriela Fryčová, Methylome profile changes in cancer cells associated with drug resistance,
status: Graduated, from: 2013 to 2016
[1] Lenka Vysloužilová, High-throughput sequencing and its use for identifying inherited causes of cardiomyopathies,
status: Graduated, from: 2013 to 2016