Oždian Tomáš Ph.D.
Email: tomas.ozdian@upol.cz
Phone: +420 585632067
Curriculum Vitae: download
PhD student working on:
- Proteomics
- Liquid chromatography / mass spectrometry applications
- Western blot
- Proteomic response of cells to anticancer drugs
Doctoral training
Cancer proteomics in clinical and experimental oncology
The thesis is focused on the detection possible biomarkers of cancer treatment efficiancy. Main task is to prepare database of proteomic profiles of current clinically available anticancer drugs.
Supervisor:
Džubák Petr M.D., Ph.D.Status:
GraduatedPublications (Impact Factor Journals):
- [7]ŠKROTT, Z., M. MISTRÍK, K. ANDERSEN, S. FRIIS, D. MAJERA, J. GURSKÝ, T. OŽDIAN, J. BARTKOVA, Z. TURI, P. MOUDRÝ, M. KRAUS, M. MEDVEDÍKOVÁ, J. VÁCLAVKOVÁ, P. DŽUBÁK, I. VROBEL, P. POUCKOVA, J. SEDLACEK, A. MIKLOVICOVA, A. KUTT, J. MATTOVA, C. DRIESSEN, Q. DOU, J. OLSEN, M. HAJDÚCH, B. CVEK, R. DESHAIES a J. BÁRTEK. Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4. Nature. 2017, 552(7684), 194-199. ISSN 0028-0836. IF: 40.137. PMID: 29211715
- [6]OŽDIAN, T., D. HOLUB, Z. MACEČKOVÁ, L. VARANASI, G. RYLOVÁ, J. ŘEHULKA, J. VÁCLAVKOVÁ, H. SLAVÍK, P. MOUDRÝ, P. ZNOJEK, J. STANKOVÁ, J.B. DE SANCTIS, M. HAJDÚCH a P. DŽUBÁK. Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells. Journal of Proteomics. 2017, 162, 73-85. ISSN 1874-3919 . IF: 3.867. PMID: 28478306
- [5]TICHÝ, M., S. SMOLEN, E. TLOUŠŤOVÁ, R. POHL, T. OŽDIAN, K. HEJTMÁNKOVÁ, B. LIŠKOVÁ, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH a M. HOCEK. Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides. Journal of Medicinal Chemistry. 2017, 60(6), 2411-2424. ISSN 0022-2623. IF: 5.589. PMID: 28221790
- [4]ŠIMKOVÁ, D., G. KHARAISHVILI, G. KOŘÍNKOVÁ, T. OŽDIAN, T. SUCHANKOVA-KLEPLOVA, T. SOUKUP, M. KŘUPKA, A. GALANDÁKOVÁ, P. DŽUBÁK, M. JANÍKOVÁ, J. NAVRATIL, Z. KAHOUNOVA, K. SOUCEK a J. BOUCHAL. The dual role of asporin in breast cancer progression. Oncotarget. 2016, 7(32), 52045-52060. ISSN 1949-2553 . IF: 5.168. PMID: 27409832
- [3]LIGASOVÁ, A., R. LIBOSKA, D. FRIEDECKÝ, K. MIČOVÁ, T. ADAM, T. OŽDIAN, I. ROSENBERG a K. KOBERNA. Dr Jekyll and Mr Hyde: A Strange Case of 5-Ethynyl-2'-deoxyuridine and 5-ethynyl-2'-deoxycytidine. Open Biology. 2016, 6: 150172, 1-11. ISSN 2046-2441. IF: 3.481. PMID: 26740587
- [2]
- [1]LEMROVÁ, B., P. SMYSLOVÁ, I. POPA, T. OŽDIAN, P. ZAJDEL a M. SOURAL. Directed Solid-Phase Synthesis of Trisubstituted Imidazo[4,5-c]pyridines and Imidazo[4,5-b]pyridines. ACS Combinatorial Science. 2014, 16(10), 558-565. ISSN 2156-8952. IF: 3.032. PMID: 25046560
Publications (Other Reviewed Journals):
- [1]OŽDIAN, T., D. HOLUB, G. RYLOVÁ, J. VÁCLAVKOVÁ, M. HAJDÚCH a P. DŽUBÁK. Porovnání hmotnostně spektrometrických přístupů v proteomickém profilování léčiv. Chemagazín. 2016, 5, 8-11. ISSN 1210-7409.
Master students mentor:
[5] Klára Brožová, Optimization and validation of FGF23 protein assay in FFPE samples,
status: Ongoing, from: 2018
status: Ongoing, from: 2018
[4] Pavlína Kalábová, Proteomics of the hair,
status: Graduated, from: 2014 to 2018
status: Graduated, from: 2014 to 2018
[3] Petra Zapletalová, Optimalization of intact protein mass spectrometry,
status: Graduated, from: 2014 to 2016
status: Graduated, from: 2014 to 2016
[2] Jarmila Stanková, Proteomic profile of CCRF-CEM cell line treated by 5-fluorouracil,
status: Graduated, from: 2014 to 2016
status: Graduated, from: 2014 to 2016
[1] Vendula Rašková, Proteomics of cervical fluid,
status: Graduated, from: 2013 to 2016
status: Graduated, from: 2013 to 2016
Bachelor students mentor:
[3] Barbora Hamerníková, Optimization and validation of FGF23 protein assay in FFPE samples,
status: Ongoing, from: 2018
status: Ongoing, from: 2018
[2] Pavlína Kalábová, The validation of differentially expressed proteins in CCRF-CEM cell line treated by oxaliplatin,
status: Graduated, from: 2013 to 2014
status: Graduated, from: 2013 to 2014
[1] Jarmila Stanková, Determination of the efficacy of 5-fluorouracil on line CCRF-CEM T,
status: Graduated, from: 2014
status: Graduated, from: 2014