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Skupiny: BAKALÁŘSKÝ STUDENT

Bakalářské studium

Preclinical development of 68Ga labelled peptides for glioblastoma imaging

This work is focused on preclinical testing of selected peptides labelled with 68Ga as potential radiodiagnostics for glioblastoma multiforme. The main goal of the study is to determine in vitro characteristics of studied peptides, their in vivo behaviour in mice and to evaluate the potential of 68Ga labelled peptides for diagnosis of glioblastoma multiforme using positron emisson tomography.

Stav: Graduated od 2014 do 2015.

Journals

GRUNER, B., J. BRYNDA, V. DAS, V. SICHA, J. ŠTĚPÁNKOVÁ, J. NEKVINDA, J. HOLUB, K. POSPISILOVA, M. FABRY, P. PACHL, V. KRAL, M. KUGLER, V. MAŠEK, M. MEDVEDÍKOVÁ, S. MATEJKOVA, A. NOVÁ, B. LIŠKOVÁ, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH, P. ŘEZÁČOVÁ
Metallacarborane Sulfamides: Unconventional, Specific, and Highly Selective Inhibitors of Carbonic Anhydrase IX. Journal of Medicinal Chemistry. 2019, 62(21), 9560-9575, ISSN: 0022-2623, PMID: 31568723,
Preclinical Evaluation of Radiolabeled Peptides for PET Imaging of Glioblastoma Multiforme. Molecules. 2019, 24(13), pii: E2496, ISSN: 1420-3049, PMID: 31288488,