Frydrych Ivo Ph.D.

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Phone: +420 585 632 145
Groups: IMTM, LEM, POSTDOCTORAL FELLOW, STAFF

Postdoctoral training

Status: Ongoing.

About me

Researcher experienced in the field of cellular biology, microscopy, and flow cytometry with the main focus on studying the mechanism of action of newly synthesized cytotoxic compounds as potential anticancer drugs. GMO advisor at IMTM. Published >25 scientific papers and books/chapters, >312 SCI citations, H-index 10.

Journals

BHOGAL, I., I. FRYDRYCH, A. MODI, V. PANKAJ, A. KUMAR, A. KHAIRNAR, V. DAS, S. ROY
Naringenin as a dual-target modulator of RAGE-NF-κB signaling and Aβ fibrillization in Alzheimer's disease: integrated computational and experimental analyses. Frontiers in Pharmacology. 2026, 17, 1901236, ISSN: 1663-9812, PMID: 42712578,  PDF.
BACHOŘÍK, J., I. FRYDRYCH, S. GURSKÁ, S. DOSTAL, J. POKORNÝ, M. HAJDÚCH, M. URBAN
New Synthetic Approach to C‑30 Ethers, Esters, and Amines of Betulin Using the Mitsunobu Reaction and Biological Evaluation of the Products. ACS Omega. 2026, 11(16), 24564-24579, ISSN: 2470-1343, PMID: 42077890,  PDF.
ORSÁG, Š., I. FRYDRYCH, B. LIŠKOVÁ, S. GURSKÁ, A. PRIBYLKA, J. HODOŇ, P. DŽUBÁK, M. HAJDÚCH, M. URBAN
Synthesis and biological evaluation of novel C-30 modified lupane triterpenoids selectively cytotoxic against cancer cells. European Journal of Medicinal Chemistry. 2025, 302 (Pt 1), 118268, ISSN: 0223-5234 , PMID: 41124881,  PDF.

Books & book chapters

FRYDRYCH, I.
Reporters based on luminescence or fluorescence detection , 1.vyd., Olomouc, Palacky University, 2021, 20, 147-152, Dedication: LO1304, ISBN: 978-80-244-6049-9,
FRYDRYCH, I.
Cell cycle analysis by flow cytometry , 1.vyd., Olomouc, Palacky University, 2021, 26, 193-200, Dedication: LO1304, ISBN: 978-80-244-6049-9,

Master mentorship

Reiterová Ivana

Preparation of cell-based reporter assay for high-throughput screening of small molecules as potential receptor for advanced glycation endproducts inhibitors

Status: Graduated from 2015 to 2017.

Bachelor mentorship

Kollárová Ema

Study of biological activity of new betulin derivatives

Status: Graduated from 2023 to 2025.

Šefčíková Pavlína

Biological Activity of Amino Derivatives of Betulin

Status: Ongoing from 2025.

WHERE TO FIND US

Hněvotínská 1333/5
779 00 Olomouc
Czech Republic

+420 585632111
+420 585632180
recepce.umtm@upol.cz
info@imtm.cz

GPS: 49° 35´ 10.1869512" N, 17° 14´ 6.292305" E

ABOUT IMTM

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