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Academic title: Mgr
Phone: +420 585632234
Groups: EXSTAFF, IMTM, LIG, POSTDOCTORAL FELLOW

Postdoctoral training

Status: Ongoing.

About me

My research is focused on mechanisms of DNA damage response (DDR) in connection to either disrupted protein homeostasis or DNA replication. Another aspect of my study aims at understanding of cancer cell vulnerabilities for better guidance of existing anticancer treatments as well as the drug-repurposing strategies.

Journals

The need for speed: drivers and consequences of accelerated replication forks. Communications Biology. 2025, 8(1), 1538, ISSN: 2399-3642, PMID: 41198817,  PDF.
DNA polymerase α-primase facilitates PARP inhibitor-induced fork acceleration and protects BRCA1-deficient cells against ssDNA gaps. Nature Communications. 2024, 15(1), 7375, ISSN: 2041-1723, PMID: 39191785,  PDF.
BUCHTOVÁ, T., L. BÉRESOVÁ, K. CHROMÁ, T. PLUHACEK, T. BERES, D. KACZOROVA, P. TARKOWSKI, J. BÁRTEK, M. MISTRÍK
Cannabis-derived products antagonize platinum drugs by altered cellular transport. Biomedicine & Pharmacotherapy. 2023, 163, 114801, ISSN: 0753-3322, PMID: 37137184,  PDF.

Bachelor mentorship

Dvořáková Markéta

Role of p21 in DNA replication

Status: Graduated from 2020 to 2021.