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Akademický titul: Mgr.
Telefon: 585632048
Skupiny: BAKALÁŘSKÝ STUDENT, DOKTORSKÝ STUDENT, IMTM, LEM, MAGISTERSKÝ STUDENT, PERSONÁL

Doktorské studium

Drug resistance mechanisms in cancer

Specializace: Molekulární a translační medicína
Stav: Ongoing od 2020.

Magisterské studium

Development and characterization of resistant cell lines to purine and pyrimidine cytotoxic drugs

Stav: Absolvoval od 2018 do 2020.

Bakalářské studium

Spectroscopic characteristics used drugs and their use in the identification of molecular targets

Stav: Graduated od 2016 do 2018.

O mně

Ph.D. student specializing in molecular and cell biology, with a primary research focus on identifying and characterizing modulators of G protein-coupled receptors (GPCRs), particularly adenosine receptor agonists and antagonists. Possesses practical experience in cancer cell biology, molecular biology techniques, and high-throughput screening methodologies.

Journals

SINKEVICIUTE, U., K. BURGETOVÁ JEČMEŇOVÁ, S. GURSKÁ, L. POSTOVA SLAVETINSKA, V. BARAN, P. POLISHCHUK, P. DŽUBÁK, M. HOCEK, M. HAJDÚCH, M. TICHÝ
Synthesis and Biological Activity of 2,6-Disubstituted and 2,6,9-Trisubstituted 7-Deazapurine Nucleobases. ChemMedChem. 2026, 21(16), e70419, ISSN: 1860-7179, PMID: 42596056,  PDF.
JURÁŠEK, M., E. DRABEROVA, J. ŘEHULKA, S. GURSKÁ, A. IVANOVA (NIKONENKO), P. POLISHCHUK, K. BURGETOVÁ JEČMEŇOVÁ, J. FAHNRICH, A. MARESOVA, J. TAUCHEN, A. REYES ROMERO, A. DÖMLING, M. HAJDÚCH, P. DRAŠAR, P. DRABER, P. DŽUBÁK
Colchicine-BODIPY Probes: Evidence for the Involvement of Intracellular Membranes in the Targeting of Colchicine to Tubulin. ACS pharmacology & translational science. 2025, 8(7), 1965-1985, ISSN: 2575-9108, PMID: 40672674,  PDF.
Click estradiol dimers with novel aromatic bridging units: synthesis and anticancer evaluation. Journal of enzyme inhibition and medicinal chemistry. 2024, 39(1), 2367139, ISSN: 1475-6366 , PMID: 38904149,  PDF.

Master mentorship

Fialová Kateřina

Optimization of High-Throughput Screening for Potential Modulators of Purinergic Receptors

Stav: Absolvoval od 2024 do 2026.

Bachelor mentorship

Fialová Kateřina

siRNA knock-down of A3 adenosine receptor

Stav: Absolvoval od 2022 do 2024.