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Akademický titul: Professor
Telefon: +420 585 632 197
Skupiny: PŘÍRODOVĚDECKÁ FAKULTA, IMTM, MEDCHEM, PERSONÁL, VEDOUCÍ

O mně

I am a scientist in the field of medicinal chemistry with current focus on natural products with various biological activities. Since 2012 I am a leader of an independent research group that currently has 2 postdocs, 4 PhD and 8 undergraduate students. Our research consists of organic synthesis, evaluation of activities and mechanism of action. I have been a PI of several grant projects from Czech Science Agency and from the Ministry of Health of the Czech Republic. Currently I serve on an evaluation panel of Czech Science Agency (P207). Earlier in my career, I was also involved in nucleic acid research, enzymology and biochemistry in general. In addition, I teach classes on bioorganic chemistry, chemical biology, and chemistry of nucleic acids. Published more than 40 papers, 3 book chapters, 4 patents, >1500 SCI citations, H-index 21.

ORCID: http://orcid.org/0000-0002-8249-028X 

Researcher ID: C-9611-2010 

Journals

PERLÍKOVÁ, P., M. KVASNICA, M. URBAN, M. HAJDÚCH, J. ŠAREK
2-Deoxyglycoside Conjugates of Lupane Triterpenoids with High Cytotoxic Activity-Synthesis, Activity, and Pharmacokinetic Profile. Bioconjugate Chemistry. 2019, 30(11), 2844-2858, ISSN: 1043-1802, PMID: 31553559,
HODOŇ, J., L. BORKOVÁ, J. POKORNÝ, A. KAZAKOVA, M. URBAN
Design and synthesis of pentacyclic triterpene conjugates and their use in medicinal research. European Journal of Medicinal Chemistry. 2019, 182, 111653, ISSN: 0223-5234, PMID: 31499360,
POKORNÝ, J., S. KRAJČOVIČOVÁ, M. HAJDÚCH, M. HOLOUBEK, S. GURSKÁ, P. DŽUBÁK, T. VOLNÁ, I. POPA, M. URBAN
Triterpenic azines, a new class of compounds with selective cytotoxicity to leukemia cells CCRF-CEM. Future Medicinal Chemistry. 2018, 10(5), 483-491, ISSN: 1756-8919, PMID: 29424548,

Bachelor mentorship

Sarková Alexandra

Derivatives of mesagenin with potential anticancer activity

Stav: Ongoing od 2025.

Kokešová Veronika

Modification of betulinic acid with triazole substituents at the C-3 position

Stav: Probíhající od 2026.

Volná místa

1 Molecular and Translational Medicine
Projekt: Research and development of agents for cancer, neurodegenerative and infectious diseases
Vedoucí: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
K dispozici: 5
Určeno pro: Doctoral training
1 Molekulární a translační medicína
Projekt: Natural compounds with anti tumor activity
Vedoucí: Urban Milan Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 místa na plný úvazek