Das Viswanath M.Sc., Ph.D.

Journals

DAS, V., M. HAJDÚCH
Oncology drug repurposing as a blueprint for Alzheimer's therapy. Alzheimer's & dementia. 2026, 12(1), e70231, ISSN: 2352-8737, PMID: 41816361,  PDF.
TANGALLAPALLI, S., R. GUNDLA, K. PAIDIKONDALA, S. GURSKÁ, N. RAMPEESA, S. ANUGU, P. DŽUBÁK, M. HAJDÚCH, V. DAS, N. KATARI
Design, synthesis, and biological evaluation of novel 3-oxo-2,3-dihydropyridazine derivatives as interleukin-2-inducible T-cell kinase (ITK) inhibitors. RSC advances. 2025, 15(55), 47565-47586, ISSN: 2046-2069, PMID: 41356712,  PDF.
ALLADI, C., I. KOZLOV, P. SKOUPILOVÁ, L. MALINA, S. ROY, V. DAS
Structural and functional insights into the selective inhibition of mutant tau aggregation by purpurin and oleocanthal in frontotemporal dementia. Protein Science. 2025, 34(9), e70240, ISSN: 0961-8368, PMID: 40862394,  PDF.

Books & book chapters

DAS, V.
Multiparametric analysis of spheroid integrity by brightfield high-content microscopy , 1.vyd., Olomouc, Palacky University, 2021, 24, 177-182, Dedication: LO1304, ISBN: 978-80-244-6049-9,
DAS, V.
Cell lines and cell culture conditions - 3D cultures , 1.vyd., Olomouc, Palacky University, 2021, 2, 15, Dedication: LO1304, ISBN: 978-80-244-6049-9,
ANNADURAI, N., V. DAS
A combination of kinetic fluorometric assay and microscopy for the screening of potential anti-tau aggregating agents, 1.vyd., Olomouc, Palacky University, 2021, 41, 317-324, Dedication: LO1304, ISBN: 978-80-244-6049-9,

Doctoral mentorship

Annadurai Narendran M.Sc., Ph.D.

Identification and Characterisation of Tau minimal regions as Potential Pharmacological Targets against Tau Spreading in Tauopathies

Stav: Absolvoval od 2015 do 2023.
Kozlov Ihor

Role of axonal transport and pathology in neurodegeneration

Stav: Probíhající od 2023.
Varečka Alexander

Dysfunction of mitochondria and microglia in tauopathies: effects of pathogenic TAU strains

Stav: Probíhající od 2025.

Master mentorship

Bechná Eliška

3D spheroids cultures of tumor cell lines for drug discovery studies

Stav: Absolvoval od 2022 do 2025.
Pavlíková Martina

Specific pharmacological modulators of tau aggregation and spreading for Alzheimer's disease preclinical studies.

Stav: Absolvoval od 2022 do 2024.
Skoupilová Patricie

Examination of mutations in tau on the activity of small molecules against prion-like tau formation in tauopathies

Stav: Absolvoval od 2023 do 2025.

Bachelor mentorship

Chudáčková Alica

Investigating the biochemical and structural alterations in tau mutants caused by VQIVYK-targeting tau inhibitors

Stav: Absolvoval od 2023 do 2025.
Vrablíková Barbora

Cytotoxicity of microtubule-stabilizing drug laulimalide in hypoxic human colorectal and cervical cancer cells

Stav: Absolvoval od 2018 do 2020.

Open positions

Projekt: The role of tumor hypoxia in the emergence of acquired resistance to drugs aimed at microtubules
Vedoucí: Das Viswanath M.Sc., Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Research and development of agents for cancer, neurodegenerative and infectious diseases
Vedoucí: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
K dispozici: 5
Určeno pro: Doktorské studium
Projekt: Role of axonal transport and pathology in neurodegeneration
Vedoucí: Das Viswanath M.Sc., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Projekt: Systems approaches to understanding aging and neurodegeneration
Vedoucí: Das Viswanath M.Sc., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Projekt: Mitochondrial and microglial dysfunction in tauopathies: effects of pathogenic TAU strains
Vedoucí: Das Viswanath M.Sc., Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 full-time position
Projekt: Investigating Effects of Aggregates of Intrinsically Disordered Proteins on Microglia: Implication for Neurodegenerative Diseases
Vedoucí: Das Viswanath M.Sc., Ph.D.
K dispozici: 1
Určeno pro: Magisterské studium
Souhrn: -
Projekt: Biochemical and cellular analysis of amyloid staining agents in models of tauopathies and synucleopathies
Vedoucí: Das Viswanath M.Sc., Ph.D.
K dispozici: 1
Určeno pro: Magisterské studium
Souhrn: -
Projekt: Generation of 3D human neuronal cultures: application to modeling CNS diseases
Vedoucí: Das Viswanath M.Sc., Ph.D.
K dispozici: 1
Určeno pro: Magisterské studium
Souhrn: -
Projekt: Efficacy of Bruton Tyrosine Kinase Inhibitors Against Neuroinflammation in Neurodegenerative Diseases
Vedoucí: Das Viswanath M.Sc., Ph.D.
K dispozici: 1
Určeno pro: Magisterské studium
Souhrn: -