Džubák Petr M.D., Ph.D.

Journals

MUDSANI, G., N. RAMPEESA, S. ANUGU, P. MUDDASANI, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH
Design, synthesis, and biological evaluation of novel azaspirooxindolinone derivatives as potent inhibitors of ITK and BTK-dependent cancers. Bioorganic & Medicinal Chemistry. 2025, 121, 118116, ISSN: 0968-0896, PMID: 40015119,  PDF.
DUMUT, D., M. HAJDÚCH, A. ZACHARIAS, Q. DUAN, I. FRYDRYCH, Z. ROŽÁNKOVÁ, M. POPPER, D. GARIC, R. PAUN, A. CENTORAME, J. SHAH, M. MISTRÍK, P. DŽUBÁK, J. DE SANCTIS, D. RADZIOCH
Diethyldithiocarbamate-copper complex ignites the tumor microenvironment through NKG2D-NKG2DL axis. Frontiers in Immunology. 2025, 16, 1491450, ISSN: 1664-3224 , PMID: 40013140,  PDF.
KAZAKOVA, A., I. FRYDRYCH, N. JAKUBCOVÁ, J. POKORNÝ, B. LIŠKOVÁ, S. GURSKÁ, R. BURIÁNOVÁ, A. PRIBYLKA, P. DŽUBÁK, M. HAJDÚCH, M. URBAN
Triterpenoid phthalimides as selective anti-cancer agents targeting mitochondrial apoptosis. European Journal of Medicinal Chemistry. 2024, ISSN: 0223-5234, PMID: 39673861,  PDF.

Intellectual property

SUBSTITUTED THIENOPYRROLOPYRIMIDINE RIBONUCLEOSIDES FOR THERAPEUTIC USE (Hocek)
  1. Published Application PCT/CZ2016/050021 under WO 2018/001393 (4.1.2018)
  2. Patent: EP 3478701. Granted: 10.8.2022. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH Marián, DŽUBÁK Petr
  3. Patent: US 10,414,788. Granted: 17.9.2019. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH Marián, DŽUBÁK Petr
  4. Patent: JP 6650074. Granted: 21.1.2020.  Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH Marián, DŽUBÁK Petr
  5. Patent: CA 3.029.170. Granted: 16.2.2021. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University, Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH Marián, DŽUBÁK Petr

Status: Terminated

15BETA-SUBSTITUTED ESTRONE DERIVATIVES AS SELECTIVE INHIBITORS OF 17BETA-HYDROXYSTEOID-DEHYDROGENASES, METHOD OF PREPARATION AND USE THEREOF (Kotora)
  1. Patent: CZ 307437. Granted: 11.7.2018. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Helmholtz Zentrum Munchen GmbH, Institute of Molecular Genetics CAS, Palacký University Olomouc. Inventors: KOTORA Martin, PRCHALOVÁ Eva, ADAMSKI Jerzy, MOLLER Gabriele, ŠTĚPÁNEK Ondřej, BARTŮNĚK Petr, SEDLÁK David, DŽUBÁK Petr, HAJDÚCH Marián
  2. Published Application PCT/CZ2017/050022 under WO 2017/211330 (14.12.2017)
  3. Published Application EP 17731057.0 under EP 3464314 (10.4.2019)
  4. Published Application AU 2017/276477 under AU 2017276477 (29.11.2018)
  5. Published Application CA 3.026.704 under CA 3026704 (14.12.2017)
  6. Published Application US 2017/16305829 under US 2019330258 (31.10.2019)

​Status: Terminated 

CULTURE DISH (Džubák)
  1. Utility Model: CZ 28806. Granted: 10.11.2015. Ownership: Palacký University Olomouc. Inventors: DŽUBÁK Petr, HAJDÚCH Marián
  2. Patent: EP 3147347. Granted: 6.5.2020. Ownership: Palacký University Olomouc. Inventors: DŽUBÁK Petr, HAJDÚCH Marián
  3. Design: CZ 36622. Granted: 28.12.2015. Ownership: Palacký University Olomouc. Inventors: DŽUBÁK Petr, HAJDÚCH Marián
  4. Registered Community Design: RCD 003039577-0001. Granted: 23.3.2016. Ownership: Palacký University Olomouc, Inventors: DŽUBÁK Petr, HAJDÚCH Marián
  5. Registered Community Design: RCD 003039577-0002. Granted: 23.3.2016. Ownership: Palacký University Olomouc, Inventors: DŽUBÁK Petr, HAJDÚCH Marián

Status: Terminated 

Doctoral mentorship

Oždian Tomáš Ph.D.

Cancer proteomics in clinical and experimental oncology

Status: Graduated from 2009 to 2016.
Balatková Pavlína

Experimental development of drugs and nanoparticles targeting prototoxic stress

Status: Ongoing from 2023.
Kroupová Denisa

Multi Omics analyzes of proximal fluids for the identification of novel biomarkers and molecular targets

Status: Ongoing from 2023.

Open positions

Project: Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Utilization of the space of unprecedented covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of molecular targets of antitumor drugs using methods of cell biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Genetic and epigenetic biomarkers of cancer diseases
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
Project: Identification of proteomic biomarkers in tears of patients with brain cancer
Supervisors: Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of proteomic biomarkers in tears of patients with neurodegenerative diseases
Supervisors: Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Antitumor drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Synthesis of kinase inhibitors and their phenotypic chemoproteomic evaluation
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Targeted approaches to covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of new derivatives targeting precancerous and tumor lesions and their mechanisms of action
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 full-time positions
Project: Genetic and epigenetic biomarkers in health and disease
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D.
Available: 5
Intended for: Doctoral training
Project: Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Identification of proteomic biomarkers in proximal fluids and tissues
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training
Project: Omic approaches in reproductive medicine
Supervisors: Džubák Petr M.D., Ph.D., Oždian Tomáš Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Anticancer drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training