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Academic title: Ing.
Phone: +420 585632186
Groups: IMTM, LEM, POSTDOCTORAL FELLOW, STAFF

Postdoctoral training

Status: Ongoing.

About me

I am a research scientist passionate for molecular and cellular biology, masive parallel sequencing and gene-expresion analysis. I always enjoy datamining of biologicaly relevant data and the comparison of data with already known information. I was involved in different studies such as wound healing characterization, experimental diabetes mellitus, effect of potentially active compounds or radiation on cells in vitro. I was responsible for a developement of a small laboratory for studing microbial biofilm in vitro. With my collegues, we are working on the developement of NGS methods for predicive diagnostics of cancer and methylome profiling. Recently we successfully released fastGEN NGS technology products together with our industrial partners. Currently we are also studying how the somatic mutations in blood cells that are appearing during aging and are connected to different vascular pathologic processeses. 

Journals

Pooling of samples to optimise SARS-CoV-2 detection in nasopharyngeal swabs and gargle lavage self-samples for covid-19 diagnostics and surveillance. Infectious Diseases. 2024, 56(7), 1-12, ISSN: 2374-4243, PMID: 38549542,  PDF.
PLEVOVA, P., J. INDRAKOVA, J. SAVIGE, P. KUHNOVA, P. TVRDA, D. CERNA, S. HILSCHEROVA, M. KUDREJOVA, D. POLENDOVA, R. JAKLOVA, M. LANGOVA, H. JAHNOVA, J. LASTUVKOVA, J. DUSEK, J. GUT, M. VLCKOVA, P. SOLAROVA, G. KRECKOVA, E. KANTOROVA, J. SOUKALOVA, R. SLAVKOVSKÝ, J. ZAPLETALOVÁ, T. TICHÝ, D. THOMASOVA
A founder COL4A4 pathogenic variant resulting in autosomal recessive Alport syndrome accounts for most genetic kidney failure in Romani people. Frontiers in Medicine. 2023, 10, 1096869, ISSN: 2296-858X, PMID: 36844206,  PDF.
Evaluation of Non-Invasive Gargle Lavage Sampling for the Detection of SARS-CoV-2 Using rRT-PCR or Antigen Assay. Viruses. 2022, 14(12), 2829, ISSN: 1999-4915, PMID: 36560833,  PDF.

Books & book chapters

DRÁBEK, J., A. JURCEKOVA, J. NOVACKOVA, J. STRÁNSKÁ, J. VRBKOVÁ, A. BARTAKOVA, L. KOTKOVÁ, M. DAJBYCHOVA, R. SLAVKOVSKÝ, T. PEXA, V. STENZL
Vybrané metody forenzní genetiky, 1.vyd., Olomouc, Palacky University, 2022, 1 s, ISBN: 978-80-244-6177-9,
Bisulfite amplicon next-generation sequencing for methylation status assessment , 1.vyd., Olomouc, Palacky University, 2021, 51, 409-422, Dedication: LO1304, ISBN: 978-80-244-6049-9,

Doctoral mentorship

Kalousová Barbora M.Sc.

Genetic biomarkers of tumors and aging

Status: Ongoing from 2019.

Master mentorship

Zermeghová Denisa

Development of new diagnostic solutions for genotyping the tumor marker BCR-ABL1

Status: Graduated from 2022 to 2025.

Věnsková Veronika

Diagnostics of mutations in RAS family oncogenes in tumors using next-generation sequencing

Status: Graduated from 2014 to 2016.

Fryčová Gabriela

Methylome profiling in cancer cells for identification of bevacizumab response biomarkers

Status: Graduated from 2016 to 2018.

Bachelor mentorship

Zermeghová Denisa

Development of new diagnostic solutions for genotyping the tumor marker BCR-ABL1

Status: Graduated from 2021 to 2022.

Fryčová Gabriela

Methylome profile changes in cancer cells associated with drug resistance

Status: Graduated from 2013 to 2016.

Vysloužilová Lenka

High-throughput sequencing and its use for identifying inherited causes of cardiomyopathies

Status: Graduated from 2013 to 2016.

Open positions

1 Biomarkers: Identification and validation
Project: Genetic and epigenetic biomarkers of cancer diseases
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
1 Molecular and Translational Medicine
Project: Genetic and epigenetic biomarkers in health and disease
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D.
Available: 5
Intended for: Doctoral training