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Telefon: +420 585 632 243
Skupiny: IMTM, LEM, PERSONÁL

O mně

Viswanath Das is a Principal Investigator and Group Leader at the Institute of Molecular and Translational Medicine, Palacký University Olomouc. His research focuses on the aggregation, prion-like seeding, and propagation of disease-associated proteins, including tau, α-synuclein, and amyloid, and on developing therapeutic strategies to inhibit these processes. He leads projects supported by the Czech Science Foundation and the Czech Ministry of Health. He has published more than 40 peer-reviewed articles and supervises postdoctoral, doctoral, and master’s researchers.

Journals

ALLADI, C., I. KOZLOV, P. SKOUPILOVÁ, L. MALINA, S. ROY, V. DAS
Structural and functional insights into the selective inhibition of mutant tau aggregation by purpurin and oleocanthal in frontotemporal dementia. Protein Science. 2025, 34(9), e70240, ISSN: 0961-8368, PMID: 40862394,  PDF.
DAS, V., S. MODARRES MOUSAVI, N. ANNADURAI, S. SUKUR, F. MEHRNEJAD, M. MORADI, L. MALINA, M. KOLARIKOVA, V. RANC, I. FRYDRYCH, R. KOURIL, S. HOSSEINKHANI, M. HAJDÚCH, M. NIKKHAH
Hydrophobic residues in the α-synuclein NAC domain drive seed-competent fibril formation and are targeted by peptide inhibitors. Federation of European Biochemical Societies. 2025, ISSN: 1742-464X, PMID: 40819250,  PDF.
DAS, V., L. DIOMEDE, L. MALINA, M. MOSCONI, N. ANNADURAI
Intrinsic aggregation and propagation of unmodified tau peptides: R2R3 as a minimal model system. Biophysical Journal. 2025, ISSN: 0006-3495 , PMID: 40515399,  PDF.

Master mentorship

Baslarová Kamila

Lipidomic analysis of exhaled breath condensate

Stav: Absolvoval od 2021 do 2023.

Martínek Jan

Proteotoxic stress in cancer cells induced by copper ionophores

Stav: Ongoing od 2026.

Kozlov Ihor Mgr.

Effect of astrocytes and glial cells on tau seeding in 3D cultures

Stav: Absolvoval od 2021 do 2023.

Volná místa

1 Chemická biologie a experimentální terapie
Projekt: The role of tumor hypoxia in the emergence of acquired resistance to drugs aimed at microtubules
Vedoucí: Das Viswanath M.Sc., Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 místo v prezenční formě studia
3 Molecular and Translational Medicine
Projekt: Role of axonal transport and pathology in neurodegeneration
Vedoucí: Das Viswanath M.Sc., Ph.D.
K dispozici: 2
Určeno pro: Doctoral training
Projekt: Systems approaches to understanding aging and neurodegeneration
Vedoucí: Das Viswanath M.Sc., Ph.D.
K dispozici: 2
Určeno pro: Doctoral training
Projekt: Research and development of agents for cancer, neurodegenerative and infectious diseases
Vedoucí: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
K dispozici: 5
Určeno pro: Doctoral training
5 Molekulární a translační medicína
Projekt: Mitochondrial and microglial dysfunction in tauopathies: effects of pathogenic TAU strains
Vedoucí: Das Viswanath M.Sc., Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 místo na plný úvazek
Projekt: Investigating Effects of Aggregates of Intrinsically Disordered Proteins on Microglia: Implication for Neurodegenerative Diseases
Vedoucí: Das Viswanath M.Sc., Ph.D.
K dispozici: 1
Určeno pro: Magisterské studium
Souhrn: -
Projekt: Biochemical and cellular analysis of amyloid staining agents in models of tauopathies and synucleopathies
Vedoucí: Das Viswanath M.Sc., Ph.D.
K dispozici: 1
Určeno pro: Magisterské studium
Souhrn: -
Projekt: Generation of 3D human neuronal cultures: application to modeling CNS diseases
Vedoucí: Das Viswanath M.Sc., Ph.D.
K dispozici: 1
Určeno pro: Magisterské studium
Souhrn: -
Projekt: Efficacy of Bruton Tyrosine Kinase Inhibitors Against Neuroinflammation in Neurodegenerative Diseases
Vedoucí: Das Viswanath M.Sc., Ph.D.
K dispozici: 1
Určeno pro: Magisterské studium
Souhrn: -