Škrott Zdeněk Ph.D.

Phone: +420 585632144

Groups: IMTM, LIG, STAFF, SUPERVISOR

Junior researcher in cellular biology and translational medicine, with ample experience in conducting and managing independent scientific projects. I am actively developing my own research program focused on the cellular response to proteotoxic stress and new techniques.

Author of 16 original scientific publications with over 1000 SCI citations. H-index 11

MAJERA, D., Z. ŠKROTT, K. CHROMÁ, J. MERCHUT-MAYA, M. MISTRÍK, J. BÁRTEK

Targeting the NPL4 Adaptor of p97/VCP Segregase by Disulfiram as an Emerging Cancer Vulnerability Evokes Replication Stress and DNA Damage while Silencing the ATR Pathway. Cells. 2020, 9(2), pii: E469, ISSN: 2073-4409, PMID: 32085572, PDF.

ŠKROTT, Z., D. MAJERA, J. GURSKÝ, T. BUCHTOVÁ, M. HAJDÚCH, M. MISTRÍK, J. BÁRTEK

Disulfiram's anti-cancer activity reflects targeting NPL4, not inhibition of aldehyde dehydrogenase. Oncogene. 2019, 38(40), 6711-6722, ISSN: 0950-9232, PMID: 31391554,

MAJERA, D., Z. ŠKROTT, J. BOUCHAL, J. BARTKOVA, D. ŠIMKOVÁ, M. GACHECHILADZE, J. STEIGEROVÁ, D. KURFÜRSTOVÁ, J. GURSKÝ, G. KOŘÍNKOVÁ, K. CWIERTKA, Z. HODNY, M. MISTRÍK, J. BÁRTEK

Targeting genotoxic and proteotoxic stress-response pathways in human prostate cancer by clinically available PARP inhibitors, vorinostat and disulfiram. The Prostate. 2018, 79(4), 352-362, ISSN: 0270-4137, PMID: 30499118,

1 Molecular and Translational Medicine

Project:	Cellular stress in health and disease
Supervisors:	Mistrík Martin Ph.D., Moudrý Pavel Ph.D., Škrott Zdeněk Ph.D.
Available:	3
Intended for:	Doctoral training

Škrott Zdeněk Ph.D.

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